| Date | Location | Result | |
| 12/02/21 | Indianapolis, Ind. | Indianapolis 3, Illinois Springfield 0 | Box score |
| 11/21/21 | Springfield, Ill. | Illinois Springfield 2, Maryville 1 (OT) | Box score |
| 11/14/21 | Indianapolis, Ind. | Indianapolis 2, Illinois Springfield 0 | Box score |
| 11/12/21 | Indianapolis, Ind. | Maryville 1, Illinois Springfield 1 (3OT) | Box score |
| 11/07/21 | Springfield, Ill. | Illinois Springfield 2, Missouri-St. Louis 0 | Box score |
| 10/31/21 | Springfield, Mo. | Illinois Springfield 1, Drury 0 | Box score |
| 10/29/21 | Rolla, Mo. | Missouri S&T 2, Illinois Springfield 0 | Box score |
| 10/24/21 | Springfield, Ill. | Illinois Springfield 2, Rockhurst 1 | Box score |
| 10/22/21 | Springfield, Ill. | Illinois Springfield 2, Southwest Baptist 1 | Box score |
| 10/17/21 | Kirksville, Mo. | Illinois Springfield 1, Truman 0 | Box score |
| 10/15/21 | Liberty, Mo. | Illinois Springfield 4, William Jewell 0 | Box score |
| 10/08/21 | Springfield, Ill. | Quincy 1, Illinois Springfield 1 (2OT) | Box score |
| 10/01/21 | Springfield, Ill. | Illinois Springfield 2, Lewis 1 | Box score |
| 09/26/21 | Lebanon, Ill. | McKendree 1, Illinois Springfield 0 | Box score |
| 09/24/21 | Evansville, Ind. | Illinois Springfield 2, Southern Indiana 1 | Box score |
| 09/19/21 | St. Charles, Mo. | Illinois Springfield 2, Lindenwood (MO) 0 | Box score |
| 09/17/21 | Springfield, Ill. | Illinois Springfield 2, Missouri-St. Louis 1 | Box score |
| 09/12/21 | Springfield, Ill. | Illinois Springfield 1, Maryville 0 | Box score |
| 09/09/21 | Kenosha, Wis. | Parkside 4, Illinois Springfield 3 (OT) | Box score |
| 09/05/21 | St. Louis, Mo. | Lynn 1, Illinois Springfield 0 (2OT) | Box score |
| 09/03/21 | Springfield, Ill. | Illinois Springfield 3, Davenport 2 | Box score |