| Date | Location | Result | |
| 10/31/21 | Springfield, Mo. | Drury 1, Illinois Springfield 0 | Box score |
| 10/29/21 | Rolla, Mo. | Missouri S&T 1, Illinois Springfield 0 (OT) | Box score |
| 10/24/21 | Springfield, Ill. | Rockhurst 1, Illinois Springfield 0 | Box score |
| 10/22/21 | Springfield, Ill. | Illinois Springfield 2, Southwest Baptist 1 | Box score |
| 10/17/21 | Kirksville, Mo. | Truman 2, Illinois Springfield 1 | Box score |
| 10/15/21 | Liberty, Mo. | Illinois Springfield 2, William Jewell 2 (2OT) | Box score |
| 10/08/21 | Springfield, Ill. | Illinois Springfield 2, Quincy 1 (OT) | Box score |
| 10/01/21 | Springfield, Ill. | Lewis 1, Illinois Springfield 0 | Box score |
| 09/26/21 | Lebanon, Ill. | McKendree 2, Illinois Springfield 1 | Box score |
| 09/24/21 | Evansville, Ind. | Illinois Springfield 2, Southern Indiana 1 | Box score |
| 09/19/21 | St Charles, Mo. | Lindenwood 2, Illinois Springfield 1 (OT) | Box score |
| 09/17/21 | Springfield, Ill. | Illinois Springfield 2, Missouri-St. Louis 1 (OT) | Box score |
| 09/12/21 | Springfield, Ill. | Illinois Springfield 1, Maryville 0 | Box score |
| 09/07/21 | Kenosha, Wis. | Illinois Springfield 2, Wis.-Parkside 0 | Box score |
| 09/04/21 | Romeoville, Ill. | Illinois Springfield 2, Tiffin 1 | Box score |
| 09/02/21 | Hammond, Ind. | Illinois Springfield 1, Purdue Northwest 1 (OT) | Box score |