| Date | Location | Result | |
| 02/27/21 | Springfield, Ill. (TRAC) | Illinois Springfield 80, Missouri S&T 71 | Box score |
| 02/20/21 | Bolivar, Mo. (Meyer Sports Center) | Southwest Baptist 73, Illinois Springfield 60 | Box score |
| 02/16/21 | Lebanon, Ill. (Melvin Price Center) | McKendree 66, Illinois Springfield 42 | Box score |
| 02/13/21 | Springfield, Ill. (TRAC) | William Jewell 73, Illinois Springfield 68 | Box score |
| 02/11/21 | Springfield, Ill. (TRAC) | Truman 72, Illinois Springfield 63 (OT) | Box score |
| 02/06/21 | Quincy, Ill. (Pepsi Arena) | Quincy 75, Illinois Springfield 64 | Box score |
| 01/30/21 | Romeoville, Ill. (Neil Carey Arena) | Illinois Springfield 78, Lewis 75 (OT) | Box score |
| 01/28/21 | Indianapolis, Ind. (Nicoson Hall) | Indianapolis 55, Illinois Springfield 43 | Box score |
| 01/23/21 | Springfield, Ill. (TRAC) | Southern Indiana 88, Illinois Springfield 69 | Box score |
| 01/21/21 | Springfield, Ill. (TRAC) | Illinois Springfield 76, McKendree 53 | Box score |
| 01/19/21 | Springfield, Ill. (TRAC) | Indianapolis 75, Illinois Springfield 74 | Box score |
| 01/16/21 | St. Louis, Mo. (Mark Twain Building) | Missouri-St. Louis 78, Illinois Springfield 50 | Box score |
| 01/14/21 | Springfield, Ill. (TRAC) | Illinois Springfield 82, Lindenwood 76 | Box score |
| 01/12/21 | Springfield, Ill. (TRAC) | Illinois Springfield 69, Lewis 54 | Box score |
| 01/09/21 | St. Louis, Mo. (Moloney Arena) | Illinois Springfield 86, Maryville 79 | Box score |
| 01/06/21 | St. Charles, Mo. (Hyland Arena) | Lindenwood 85, Illinois Springfield 75 | Box score |
| 01/03/21 | Rolla, Mo. (Gibson Arena) | Illinois Springfield 84, Missouri S&T 78 | Box score |
| 12/05/20 | Springfield, Ill. (TRAC) | Maryville 61, Illinois Springfield 60 | Box score |
| 12/03/20 | Kansas City, Mo. (Mason-Halpin) | Rockhurst 74, Illinois Springfield 68 | Box score |
| 11/27/20 | Springfield, Ill. | Illinois Springfield 89, Quincy 82 | Box score |